A clinical trial to study the effect of two therapies, Virechana Karma and Jalaukavacharana along with atrushadi Kashaya Pana in Ek-Kushtha (Psoriasis)

Not yet recruiting

Conditions: Psoriasis, unspecified. Ayurveda Condition: EKAKUSHTHAH,

Registration Number: CTRI/2023/10/059004

Lead Sponsor: Uttarakhand Ayurved University

Brief Summary: Skin disorders are one of the burning problems of the modern era and Psoriasis is one of them. Psoriasis is a chronic, non-infectious, inflammatory and an auto-immune disorder characterized by sharply demarcated erythematous plaques with mica like silvery scales. However, Psoriasis is a painless condition. It occurs primarily on elbow, knee, and scalp. The exact etiology is unknown but factor, which are responsible for wide spread prevalence of this disease are psychological stress and lifestyle. Other triggering factors include infection, drug, trauma etc.

In Ayurveda all skin disorders have been described under the Kushtha. Kushtha has been considered one among the Ashtamahagada in Ayurveda and have been stated as Aupsaragika Roga. It is also mentioned under Raktapradoshaja Vikara and is divided into 2 types as Maha Kushtha and Kshudra Kustha. According to Acharya Charaka Ek-Kushtha is due to vitiation of Vata & Kapha, and the symptoms has described as- Aswedanam, Mahavastu, and Matsyashaklopum.

Incidence of psoriasis is increasing rapidly; there is need to find out the treatment that can help in prevention and cure of the disease. Currently available management options like corticosteroids, PUVA are not much promising and are reported to have associated adverse effects. Ayurvedic approach in the disease is by pacifying the Doshas, paying special attention to Vata-Kapha Shamana and Rakta Dushti Shodhana. So, two important Karma Virechana and Jalaukavacharana are chosen

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patient having sign and symptoms of Ek-Kushtha (Psoriasis).
Patient of age between 16 years to 60 years will be included.
Patient willing to take part in Virechana Karma.
Patient willing to take part in Jalaukavacharana.

Exclusion Criteria

Known case of malignancy, IHD, CHF, and any other vascular disease.
Uncontrolled diabetes mellitus, hypertension and other life threatening and complicated diseases.
Pregnant and lactating women.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
No improvement: 0-25%	0th, 25th, 45th day
Mild improvement: 26-50%	0th, 25th, 45th day
Moderate improvement: 51-75%	0th, 25th, 45th day
Marked improvement: 76-100%	0th, 25th, 45th day

Secondary Outcome Measures

Name	Time	Method
Exacerbation in signs & symptoms	45 days

Trial Locations

Locations (1): Rishikul Campus, UAU Haridwar
🇮🇳
Hardwar, UTTARANCHAL, India
Rishikul Campus, UAU Haridwar
🇮🇳Hardwar, UTTARANCHAL, India
Dr Anirudh
Principal investigator
9548493223
sainianirudh007@gmail.com