The effect of isotretinoin in the treatment of acne
Not Applicable
- Conditions
- Acne.Acne Vulgaris
- Registration Number
- IRCT2017052725407N2
- Lead Sponsor
- Jahrom University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 36
Inclusion Criteria
18-30 years old women with moderate to severe acne vulgaris.
Exclusion criteria: pregnancy; hypersensitivity to parabens; poly cystic ovarian disease; recent history of mood or depressive disorders; thyroid disease; pituitary disease and use of Finasteride; retinoids or hormonal contraception within three months of enrollment.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dihydrotestosterone. Timepoint: Before and after the intervention. Method of measurement: ng/ml.;17-hydroxyprogestrone. Timepoint: Before and after the intervention. Method of measurement: ng/ml.;Testosterone. Timepoint: Before and after the intervention. Method of measurement: ng/ml.;Dehydroepiandrosterone. Timepoint: Before and after the intervention. Method of measurement: ng/ml.;Free testosterone. Timepoint: Before and after the intervention. Method of measurement: ng/ml.;Luteinizing hormone. Timepoint: Before and after the intervention. Method of measurement: ng/ml.;Follicle stimulating hormone. Timepoint: Before and after the intervention. Method of measurement: ng/ml.;Prolactin. Timepoint: Before and after the intervention. Method of measurement: ng/ml.
- Secondary Outcome Measures
Name Time Method