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To Analyze the Effect of Bone healing in Periapical Defects using Simvastatin, Hydroxyappatite and PRF as bone grafts by clinicaly and radiographicaly.

Not Applicable
Completed
Conditions
Health Condition 1: null- chronic apical periodontitis
Registration Number
CTRI/2017/06/008881
Lead Sponsor
Dr Sweety Gupta
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
33
Inclusion Criteria

1- patients with chronic periapical pathology

2- Aged 18 â?? 40 yrs

3- Mandibular and maxillary anterior teeth

Exclusion Criteria

1-Previous history of periapical surgery

2-Smokers and other abusive habits

3-Systemically compromised patients

4-Patients on statins

5-Patients not willing for treatment

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary outcome will be bony healing of the <br/ ><br>periapical area which will be evaluated after 3, 6 <br/ ><br>and 12 months postoperatively with <br/ ><br>CBCT <br/ ><br>Timepoint: 6 months <br/ ><br>and 12 months postoperatively with CBCT <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
swelling, pain, pus discharge or presence of sinus will be evaluated after 1 week clinically post operativelyTimepoint: 1 week postoperatively
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