Compass - Comorbidity of Major Depressive Disorder and Autism Spectrum Disorders
- Conditions
- ASDAutism10012562
- Registration Number
- NL-OMON43350
- Lead Sponsor
- Radboudumc
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 192
Inclusion criteria patients:
- ASD diagnosis based on the current Dutch guidelines
- MDD diagnosis based on DSM-IV criteria using the Structured Clinical Interview for DSM Disorders I (SCID-I).
- Age 18-65
- IQ>70;Inclusion criteria healthy controls:
- Age 18-65
- No history of psychiatric disorders
Exclusion criteria patients:
- Sensorimotor handicaps
- Impaired vision or color blindness
- Inadequate command of the Dutch language
- Mentally incompetent to sign informed consent;Exclusion criteria all:
- Exclusion criteria specifically for the MRI section:
o Metal objects in the body (excluding dental fillings)
o Jewelry or piercings than cannot be removed
o Brain surgery
o Epilepsy
o Claustrophobia
o Pregnancy
o Ferromagnetic implants or pacemakers
o Inability to lie still for one hour
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main objective of this project is to increase knowledge about the specific<br /><br>and shared mechanisms of ASD and MDD on a behavioral, cognitive and<br /><br>neurobiological level.</p><br>
- Secondary Outcome Measures
Name Time Method