CTRI/2022/09/045700招募中4 期
Comparison of furosemide infusion alone with albumin-furosemide combination for the treatment of refractory edema in children with nephrotic syndrome: a randomized controlled non-inferiority trial
试验速览
- 阶段
- 4 期
- 状态
- 招募中
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Children, between 1-12 years of age, with nephrotic syndrome and refractory edema ( <1% weight loss per day for 5 consecutive days or <5% cumulative weight loss by 5th day of hospitalization after receiving maximum oral dose of furosemide, hydrochlorothiazide or metolazone and IV furosemide bolus in sequence) will be enrolled for the study
排除标准
- •1.Known secondary causes of nephrotic syndrome or with features of glomerulonephritis; like gross hematuria, hypertension, oliguria and deranged kidney function.
- •2.Children with acute diarrhoea
- •3.Clinical features of hypovolemia
- •4.With AKI stage II or III according to KDIGO definition and classification criteria for AKI
- •5.Children with severe systemic infections; like pneumonia, peritonitis, cellulitis or sepsis
- •6.Children with respiratory distress
研究者
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