MedPath

Safety Study of F2695 SR in Major Depressive Disorder

Phase 3
Completed
Conditions
Major Depressive Disorder
Interventions
Drug: F2695 SR
Registration Number
NCT01034267
Lead Sponsor
Forest Laboratories
Brief Summary

The purpose of this study is to evaluate the long- term safety of F2695-SR in the treatment of adults with major depressive disorder.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
828
Inclusion Criteria
  • Completed 1 of the lead-in studies LVM-MD-01, LVM-MD-02, or LVM-MD-03
  • Have normal examination findings at the final visit of the lead-in study
  • Have a negative serum pregnancy test at the final visit of the lead-in study if a woman of child-bearing potential
Exclusion Criteria
  • Any exclusionary psychiatric or medical condition that developed during the lead in study
  • Patients considered a suicide risk
  • Women who are pregnant, breastfeeding, or planning to become during the study OR are sexually active and not currently using a medically acceptable method of contraception

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
1F2695 SR(Open-label) F2695 SR capsules, oral administration, once daily, flexible dosing
Primary Outcome Measures
NameTimeMethod
Adverse events, clinical laboratory tests, vital sign measurements, electrocardiograms, physical examinations, Columbia-Suicide Severity Rating Scale48 weeks
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (68)

Forest Investigative Site 9

🇺🇸

Staten Island, New York, United States

Forest Investigative Site 54

🇺🇸

Allentown, Pennsylvania, United States

Forest Investigative Site 47

🇺🇸

Dallas, Texas, United States

Forest Investigative Site 32

🇺🇸

Fall River, Massachusetts, United States

Forest Investigative Site 33

🇺🇸

Chicago, Illinois, United States

Forest Investigative Site 41

🇺🇸

Seattle, Washington, United States

Forest Investigative Site 55

🇺🇸

Dothan, Alabama, United States

Forest Investigative Site 22

🇺🇸

Oceanside, California, United States

Forest Investigative Site 29

🇺🇸

Scottsdale, Arizona, United States

Forest Investigative Site 31

🇺🇸

Beverly Hills, California, United States

Forest Investigative Site 3

🇺🇸

Costa Mesa, California, United States

Forest Investigative Site 12

🇺🇸

Encino, California, United States

Forest Investigative Site 6

🇺🇸

Escondido, California, United States

Forest Investigative Site 60

🇺🇸

Boca Raton, Florida, United States

Forest Investigative Site 38

🇺🇸

Sherman Oaks, California, United States

Forest Investigative Site 28

🇺🇸

Denver, Colorado, United States

Forest Investigative Site 53

🇺🇸

Ocala, Florida, United States

Forest Investigative Site 65

🇺🇸

Highlands Ranch, Colorado, United States

Forest Investigative Site 30

🇺🇸

Cromwell, Connecticut, United States

Forest Investigative Site 57

🇺🇸

Boca Raton, Florida, United States

Forest Investigative Site 34

🇺🇸

Fort Myers, Florida, United States

Forest Investigative Site 18

🇺🇸

Coral Springs, Florida, United States

Forest Investigative Site 59

🇺🇸

Winter Park, Florida, United States

Forest Investigative Site 13

🇺🇸

Orlando, Florida, United States

Forest Investigative Site 52

🇺🇸

Shreveport, Louisiana, United States

Forest Investigative Site 15

🇺🇸

East Lansing, Michigan, United States

Forest Investigative Site 61

🇺🇸

Orlando, Florida, United States

Forest Investigative Site 27

🇺🇸

West Palm Beach, Florida, United States

Forest Investigative Site 23

🇺🇸

Hoffman Estates, Illinois, United States

Forest Investigative Site 70

🇺🇸

Atlanta, Georgia, United States

Forest Investigative Site 71

🇺🇸

Prairie Village, Kansas, United States

Forest Investigative Site 63

🇺🇸

Indianapolis, Indiana, United States

Forest Investigative Site 5

🇺🇸

Wichita, Kansas, United States

Forest Investigative Site 37

🇺🇸

Rockville, Maryland, United States

Forest Investigative Site 1

🇺🇸

Baltimore, Maryland, United States

Forest Investigative Site 2

🇺🇸

Glen Burnie, Maryland, United States

Forest Investigative Site 42

🇺🇸

Brooklyn, New York, United States

Forest Investigative Site 4

🇺🇸

Mount Kisco, New York, United States

Forest Investigative Site 16

🇺🇸

New York, New York, United States

Forest Investigative Site 25

🇺🇸

Canton, Ohio, United States

Forest Investigative Site 39

🇺🇸

New York, New York, United States

Forest Investigative Site 46

🇺🇸

Raleigh, North Carolina, United States

Forest Investigative Site 14

🇺🇸

Media, Pennsylvania, United States

Forest Investigative Site 24

🇺🇸

Philadelphia, Pennsylvania, United States

Forest Investigative Site 56

🇺🇸

Oklahoma City, Oklahoma, United States

Forest Investigative Site 10

🇺🇸

Dayton, Ohio, United States

Forest Investigative Site 67

🇺🇸

Oklahoma City, Oklahoma, United States

Forest Investigative Site 40

🇺🇸

Portland, Oregon, United States

Forest Investigative Site 58

🇺🇸

Salem, Oregon, United States

Forest Investigative Site 62

🇺🇸

San Antonio, Texas, United States

Forest Investigative Site 43

🇺🇸

Norristown, Pennsylvania, United States

Forest Investigative Site 20

🇺🇸

Dallas, Texas, United States

Forest Investigative Site 26

🇺🇸

Memphis, Tennessee, United States

Forest Investigative Site 7

🇺🇸

San Antonio, Texas, United States

Forest Investigative Site 8

🇺🇸

Woodstock, Vermont, United States

Forest Investigative Site 68

🇺🇸

Virginia Beach, Virginia, United States

Forest Investigative Site 19

🇺🇸

Bellevue, Washington, United States

Forest Investigative Site 44

🇺🇸

Lincoln, Rhode Island, United States

Forest Investigative Site 64

🇺🇸

Gainesville, Florida, United States

Forest Investigative Site 45

🇺🇸

Hallandale Beach, Florida, United States

Forest Investigative Site 66

🇺🇸

Smyrna, Georgia, United States

Forest Investigative Site 50

🇺🇸

Oak Brook, Illinois, United States

Forest Investigative Site 51

🇺🇸

Brooklyn, New York, United States

Forest Investigative Site 21

🇺🇸

Willingboro, New Jersey, United States

Forest Investigative Site 69

🇺🇸

Spokane, Washington, United States

Forest Investigative Site 36

🇺🇸

Denver, Colorado, United States

Forest Investigative Site 17

🇺🇸

Jacksonville, Florida, United States

Forest Investigative Site 35

🇺🇸

Cherry Hill, New Jersey, United States

© Copyright 2025. All Rights Reserved by MedPath