Detection of task-specific high-frequency oscillatory activity in patients with idiopathic Parkinson syndrome

Not Applicable

• Conditions: G20.1

• Registration Number: DRKS00023347
• Lead Sponsor: niklinik Leipzig Klinik für Neurologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-19
• Study Completion: 2022-08-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Female and male participants between 30 and 80 years of age; normal vision (also corrected, e.g. by glasses/contact lenses) according to self-disclosure, signing of consent form; specific for MRI: participation in a detailed explanation of possible contraindications and risks during an MRI examination at 3 Tesla, signing of consent forms, specific for Parkinson's patients: Confirmed diagnosis of an idiopathic Parkinson's syndrome with mild to severe bradykinesis and/or rigor as predominant symptomatology (Hoehn & Yahr 1 - 4)

Exclusion Criteria

Non-consent or inability of the subject to consent to participate in the study; Alcohol or drug abuse; Other neurological diseases with the exception of idiopathic Parkinson's syndrome, psychiatric diseases; Complex and extensive medication which, in the opinion of the investigator, influences the performance of the experiments; Claustrophobia; Pregnancy according to self-disclosure; Specific for MRI: Contraindication for MRI examination;
Specific for Parkinson's patients: pronounced rest tremor

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in oscillatory activity in the on and off state of dopaminergic medication in patients with idiopathic Parkinson's syndrome and in comparison to healthy controls

Secondary Outcome Measures

Name	Time	Method
no secondary outcome