Postpartum Thyroid Measures and Mood
- Conditions
- Postpartum Depression
- Registration Number
- NCT00565032
- Lead Sponsor
- Oklahoma State University Center for Health Sciences
- Brief Summary
Women with abnormal serum thyroid antibody levels or abnormal TSH and/or T4 values are more likely than their normal counterparts to have higher scores on a common postpartum depression screening test.
- Detailed Description
This small pilot study was an attempt to corroborate a relationship between quantified mood and thyroid measures, using the numerical scores obtained from a common depression screen, the Edinburgh Postnatal Depression Scale (EPDS), as a continuum. Mood scores were compared with presence of thyroid autoantibodies and plasma concentrations of free T4 and TSH.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 75
-
Over 18 years of age
-
In third trimester of pregnancy when recruited
-
Negative for the following drugs detected by a urine drug screen:
- Amphetamines
- Barbiturates
- Benzodiazepines
- Cocaine
- Opiates
- Phencyclidine metabolites (PCP), and tricyclic antidepressants
- Vaginal delivery
- Screened negative for major depressive disorder on the Edinburgh Postnatal Depression Scale (EPDS) at her prenatal enrollment in the study
- Receiving a score of 12 or lower out of a possible 30
-
Under age 18
-
Positive for any of the following drugs:
- Amphetamines
- Barbiturates
- Benzodiazepines
- Cocaine
- Opiates
- Phencyclidine metabolites (PCP), and tricyclic antidepressants
- Cesarean delivery
- EPDS score over 12 at prenatal screening test
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Numerical score on the Edinburgh Postnatal Depression Scale seven weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Oklahoma State University Center for Health Sciences Houston Park Obstetrics Clinic
🇺🇸Tulsa, Oklahoma, United States
Oklahoma State University Center for Health Sciences Houston Park Obstetrics Clinic🇺🇸Tulsa, Oklahoma, United States