PRImary care Streptococcal Management study (PRISM) Rapid tests for streptococcal sore throat

Completed

• Conditions: ower Respiratory Tract Infections (LRTI); Respiratory; Lower Respiratory Tract Infections

• Registration Number: ISRCTN32027234
• Lead Sponsor: niversity of Southampton (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-02-27
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 2026

Inclusion Criteria

Phase 1: Adults/children aged 5 and over presenting with acute sore throat ( 2 weeks or less; and with some abnormality of examination of the throat ? i.e. erythema and/or pus).
Phase 2: . Previously well subjects aged 3 years and over with acute illness (2 weeks or less), presenting with sore throat as the main symptom, with an abnormal examination of the pharynx.

Exclusion Criteria

Phase 1:
1. Other non infective causes of sore throat (e.g. apthous ulceration, candida, drugs)
2. Unable to consent (e.g. dementia, uncontrolled psychosis)
Phase 2:
1. Quinsy, previous rheumatic fever, glomerulonephritis.
2. Serious chronic disorders where antibiotics are needed (e.g. cystic fibrosis, valvular heart disease), or mental health problems (e.g. learning difficulties - unable to complete outcome measures).

Study & Design

• Study Type: Interventional
• Study Design: Not specified