Epidermoid Cancer Development in Esophageal Achalasia
- Conditions
- AchalasiaEpidermoid Carcinoma
- Registration Number
- NCT03546998
- Lead Sponsor
- Sandro Mattioli
- Brief Summary
Esophageal achalasia is a precancerous condition for epidermoid carcinoma; incidence and risk factors for cancer development are not defined. Incidence and risk factors for epidermoid carcinoma development in achalasia patients were investigated.
- Detailed Description
In order to define incidence and risk factors for epidermoid carcinoma 681 patients affected by esophageal achalasia observed since 1973 were followed up with no time limits according to a prospective follow-up protocol. The local institutional review board approved using the database from the division of thoracic surgery for research purposes. Clinical, radiological and endoscopic data of achalasia patients were collected and analyzed.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 681
- diagnosis of primary esophageal achalasia achieved by means of radiology, endoscopy and manometry
- pseudoachalasia
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Detection of epidermoid carcinoma of the esophagus 1 year Detection of epidermoid carcinoma of the esophagus by means of upper GI endoscopy
- Secondary Outcome Measures
Name Time Method Result of achalasia treatment by investigating dysphagia and gastro-esophageal reflux 1 year Result of achalasia treatment assessed by means of semiquantitative grading scales of dysphagia and gastro-esophageal reflux
Trial Locations
- Locations (1)
Division of Thoracic Surgery Maria Cecilia Hospital
🇮🇹Cotignola, RA, Italy