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The Determinants of Fertility Preservation in TRANSgender Patients.

Recruiting
Conditions
Fertility Preservation
Transgender
Transgenderism
Interventions
Behavioral: No intervention.
Registration Number
NCT06074796
Lead Sponsor
Central Hospital, Nancy, France
Brief Summary

The study is monocentric, retrospective, non-interventional and does not involve human subjects.

The main objective is to compare the profiles of transgender patients who undergo fertility preservation with those who do not.

The secondary objectives are to define the rate of recourse to fertility preservation, determine the proportion of patients wishing to become parents.

Statistical analysis will be carried out with a view to highlighting significant determinants in transgender patients by comparing those who undergo fertility preservation with those who do not.

The data will have been collected during routine consultations as part of the transition process for transgender patients. This is taking place in the reproductive medicine department of the regional university hospital centre in Nancy.

Detailed Description

This study aims to assess the determinants of fertility preservation (FP) among transgender patients at the University Regional Hospital Center (CHRU) of Nancy. The secondary objective was to establish a database to gain a deeper understanding of the challenges related to fertility preservation in the context of a transition project and thus provide more tailored support to transgender patients.

The primary endpoint is the significativity of profiles elements of transgender patients who undergo fertility preservation with those who do not.

It may help the understanding of the determinants of fertility preservation in transgender patients.

We expect to include between 200 and 300 patients. The data will be transcribed onto the anonymised data collection Excel sheet. Statistical analysis of qualitative and quantitative data will be carried out with a view to highlighting significant determinants in transgender patients by comparing those who undergo fertility preservation with those who do not.

The study is monocentric, retrospective, non-interventional and does not involve human subjects. In fact, this research is based on existing data, extracted from patient files in the médifirst software. The data will have been collected during routine consultations as part of the transition process for transgender patients. This is taking place in the reproductive medicine department of the regional university hospital centre in Nancy.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
230
Inclusion Criteria
  • Transgender patients who consulted the Assisted Reproductive Technology centre of the Nancy Regional University Hospital, between 1st January 2020 and 30th June 2023. The consultations occurred for the start of transition care, for follow-up or for a parenting project for transgender patients.
Exclusion Criteria
  • minors
  • patients under guardianship or under tutelage

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Transgender patientsNo intervention.Patients included are transgender patients who have had routine consultations as part of the transition process for transgender patients, done in the reproductive medicine department of the regional university hospital centre in Nancy. Exclusion criteria : minors, patients under guardianship or trusteeship. French laws allow embryo transfer until 45 years for women and sperm reuse up to 60 years for men, so patients older have been excluded.
Primary Outcome Measures
NameTimeMethod
significant result p < 0.05 of qualitative and quantitative dataStatistiques Will be done by December 2023.

The significance of statistical tests (significant result p \< 0.05) will show whether or not there are emerging determinants in each of the 2 groups: fertility preservation done / not done. Qualitative data will be available in the medical files created during the appointments of transgender patients who have consulted the Reproductive Medicine Department.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Centre AMP Maternité Régionale de Nancy

🇫🇷

Nancy, France

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