Oxygen Consumption (VO2), Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit (ICU)

• Conditions: Beademde patienten; Mechanically ventilated patients

• Registration Number: NL-OMON56162
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

18 years of age ore older
> 24 hours mechanically ventilated
- Eligible for a spontaneous breathing trial according to the clinical team
- Regular SBT (Regulier SBT) according to the LUMC protocol
- Hemodynamically stable
- Esophageal Catheter in situ

Exclusion Criteria

Known pregnancy
Severe COPD (Gold class IV) if it results in a non regular SBT according to the
LUMC protocol.
Heart failure (LVEF < 30%) if it results in a non regular SBT according to the
LUMC protocol.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Weaning- or extubation failure (or success) after a successful SBT.<br /><br>Furthermore, the differences between start and end of SBT and absolute values<br /><br>of the following parameters: VO2, Pressure Swings, Work of Breathing, Pressure<br /><br>Time Product, Rapid Shallow Breathing Index. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>