Colchicine in patients with myocardial infarctio
Phase 2
- Conditions
- Acute myocardial infarction.ST elevation (STEMI) and non-ST elevation (NSTEMI) myocardial infarction
- Registration Number
- IRCT20210423051047N2
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
A patient over 20 years of age with ST Elevated MI who is a candidate for Primary PCI and presented within less than 12 hours of the onset of pain
Exclusion Criteria
Cardiogenic shock or hemodynamic instability
Known hypersensitivity to colchicine
Patients with a history of chronic kidney and liver disease
Thrombocytopenia or leukopenia
Pregnant or lactating women
Patients receiving CYP3A4 inhibitors
Patients already taking colchicine
Patients who have evidence of active or inflammatory infection
Patients with a history of AF or MI
Patients with a history of CABG
MI patients in the field of stent thrombosis
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment of interleukin 1B levels. Timepoint: 24 hours after intervention. Method of measurement: Elisa Kit.
- Secondary Outcome Measures
Name Time Method Evaluation of recurrent myocardial infarction. Timepoint: On a daily basis from the start of the intervention. Method of measurement: Follow-up of symptoms of myocardial infarction.