Development of a Minimally Invasive Cardiac Output Monitoring Device for Critically Ill Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiac Event
- Sponsor
- University of Michigan
- Enrollment
- 77
- Locations
- 1
- Primary Endpoint
- Establishment of a Dataset to Create an Algorithm to Measure Cardiac Output
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
The overall goal of this collaborative study is to advance the novel "pulse contour analysis" to the point at which it can be incorporated into a real-time device. The specific objective is to establish an auto-calibration algorithm that conveniently yields cardiac output (CO) in units of liters-per-minute. To achieve this objective, the waveforms for analysis and reference pulmonary artery catheter CO measurements will be recorded from critically ill patients and then analyzed off-line at Retia Medical. Successful completion of this study may ultimately help lead to improved outcomes of critically ill patients.
Investigators
Dr. James M. Blum
Assistant Professor Of Anesthesiology, Director of Critical Care Research
University of Michigan
Eligibility Criteria
Inclusion Criteria
- •All adult patients admitted to the University of Michigan ICU following cardiac surgery with both a pulmonary and radial artery catheter.
Exclusion Criteria
- •Adult patients with mechanical cardiac support including intra-aortic balloon pumps, LVAD, or ECMO, and persistent ventricular arrhythmias.
Outcomes
Primary Outcomes
Establishment of a Dataset to Create an Algorithm to Measure Cardiac Output
Time Frame: 8 hours post cardiac surgery
The primary outcome of this work is to establish a dataset that would enable the calculation of a predicted cardiac output using waveform analysis from multiple sensors. The primary outcome of this work is the number of subjects that successfully contributed data.