Dietary Supplements and Aging Muscle: Specific Amino Acids to Combat Sarcopenia

University of Alabama at Birmingham1 site in 1 country36 target enrollmentFebruary 2010

ConditionsSarcopenia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Sarcopenia
Sponsor: University of Alabama at Birmingham
Enrollment: 36
Locations: 1
Primary Endpoint: Fat-free mass as determined by a four-compartment model of body composition
Status: Completed
Last Updated: 14 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether older adults (ages 65-89) who consume the dietary supplement Juven (Abbott Laboratories) versus placebo for 6 months will demonstrate increases in fat-free mass, muscle volume,and physical function.

Registry

clinicaltrials.gov

Start Date

February 2010

End Date

December 2011

Last Updated

14 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of Alabama at Birmingham

Responsible Party

Principal Investigator

Amy Ellis

Registered Dietitian; Graduate Fellow

University of Alabama at Birmingham

Eligibility Criteria

Inclusion Criteria

•Ages 65-89
•Ambulatory

Exclusion Criteria

•Cognitive impairment
•History of renal or hepatic disease
•History of hypotension
•History of peripheral artery disease
•Uncontrolled hypertension
•Uncontrolled diabetes
•Self-reported claustrophobia
•Current smoker
•Steroid or androgen use with the previous 3 months
•Individuals with pacemakers and defibrillators

Outcomes

Primary Outcomes

Fat-free mass as determined by a four-compartment model of body composition

Time Frame: Baseline, 3-months, 6-months

Secondary Outcomes

Appendicular lean mass as determined by dual energy X-ray absorptiometry(Baseline, 3-months, 6-months)
Muscle volume as determined by magnetic resonance imaging(Baseline and 6-months)
Physical function as determined by questionnaire and a battery of physical performance tests(Baseline and 6 months)