NCT01145131
Completed
Not Applicable
Dietary Interventions for Muscle Mass
ConditionsAging
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aging
- Sponsor
- Maastricht University Medical Center
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Muscle protein synthesis
- Status
- Completed
- Last Updated
- 14 years ago
Overview
Brief Summary
Dietary intervention to prevent sarcopenia in elderly people. The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate the muscle protein growth in elderly people.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Non-obese male subjects (BMI\<30) between the age of 65-85 years.
Exclusion Criteria
- •Type II diabetes or other known diseases, use of medication, female, other ages or BMI than indicated above, participation in any regular exercise program.
Outcomes
Primary Outcomes
Muscle protein synthesis
Time Frame: 6 h postprandial period
Muscle protein synthesis will be expressed as fractional synthetic rate (FSR) by dividing the increment in enrichment in the product, i.e. protein-bound D5phe tracer, by the enrichment of the precursor (=plasma availability).
Secondary Outcomes
- Dietary amino acid plasma availability(6h postprandial period)
Study Sites (1)
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