Dietary Interventions for Muscle Mass

Not Applicable

Completed

• Conditions: Aging

• Registration Number: NCT01145131
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

Dietary intervention to prevent sarcopenia in elderly people. The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate the muscle protein growth in elderly people.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2010-06-15
• Study First Submitted QC: 2010-06-15
• Study First Posted: 2010-06-16
• Study Start: 2011-05
• Primary Completion: 2011-06
• Study Completion: 2011-06
• Status Verified: 2011-09
• Last Update Submitted: 2011-09-13
• Last Update Posted: 2011-09-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 12

Inclusion Criteria

• Non-obese male subjects (BMI<30) between the age of 65-85 years.

Exclusion Criteria

• Type II diabetes or other known diseases, use of medication, female, other ages or BMI than indicated above, participation in any regular exercise program.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Muscle protein synthesis	6 h postprandial period	Muscle protein synthesis will be expressed as fractional synthetic rate (FSR) by dividing the increment in enrichment in the product, i.e. protein-bound D5phe tracer, by the enrichment of the precursor (=plasma availability).

Secondary Outcome Measures

Name	Time	Method
Dietary amino acid plasma availability	6h postprandial period	The exogenous rate of phenylalanine appearance will be used to assess the bio-availability of dietary-protein derived amino acids in the circulation during the 6h postprandial period following meat intake

Trial Locations

Locations (1)

Universiteit Maastricht, Bewegingswetenschappen; 🇳🇱 Maastricht, Limburg, Netherlands