Comparison of efficacy of three different local anaesthetic mixtures for upper limb surgeries under usg guided supraclavicular brachial plexus block a randomised controlled trial

Combining local anesthetics (LAs) to achieve both rapid onset and prolonged duration has been practiced for over 50 years. While some studies have shown benefits—such as faster onset with a 40 mL mixture of mepivacaine and bupivacaine in infraclavicular blocks—others found no advantage at lower volumes (e.g., 30 mL in interscalene blocks). Advances in ultrasound-guided techniques have enabled effective brachial plexus blocks with lower volumes (10–20 mL), especially in the supraclavicular region. However, most studies focus on higher volumes. This study aims to evaluate the characteristics of a 20 mL mixture of local anesthetics for ultrasound-guided supraclavicular brachial plexus block.