The Role of Radial Peripapillary Vessel Density in Irvine-gass Syndrome
- Conditions
- Macular EdemaCataract
- Interventions
- Diagnostic Test: OCTA
- Registration Number
- NCT06436170
- Lead Sponsor
- Federico II University
- Brief Summary
Pseudophakic cystoid macular edema (PCME), also known as Irvine-Gass syndrome (IGS), is an accumulation of fluid in the macula that occurs after cataract surgery, with an early or late presentation (cut-off 3 months) . It is the most common cause of decreased vision after uneventful phacoemulsification, with a rare incidence of 0.1-2.35% for clinically significant PCME .
Macular edema in IGS can be diagnosed and classified by optical coherence tomography (OCT), which enables its morphologic assessment. Fluorescein angiography (FA) is the gold standard to perform differential diagnosis for macular edema.
To date, OCT angiography (OCTA) has been proposed to study various retinal vascular diseases. In contrast to FA, OCTA is able to visualize Radial peripapillary vessel density (RCP).
The aim of this study was to investigate abnormalities in the vascular network of the optic nerve head in patients with IGS compared to healthy eyes, using OCT-A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Clinical diagnosis of PCME Cataract surgery
diabetes vein occlusion uveitis vasculitis age-related macular degeneration hereditary macular dystrophy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 30 patiens with IGS mean age 70 ±6 OCTA - 30 healthy controls mean age 70 ±5 OCTA -
- Primary Outcome Measures
Name Time Method the role of OCTA in diagnosis of IGS 10 months To evaluate the vascolarization of RPC in IGS
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Federico II of Naples
🇮🇹Naples, Italy