Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms

Completed

• Conditions: Unruptured Intracranial Aneurysms

• Registration Number: NCT01490463
• Lead Sponsor: Johann Wolfgang Goethe University Hospital

Brief Summary

The purpose of this study is to determine the incidence and impact of brain lesions in MRI after coiling and clipping of unruptured intracranial aneurysms on clinical and neurological outcome of patients.

Detailed Description

Silent ischemic lesions after treatment of unruptured intracranial aneurysm (UIA) might alter patients' clinical and neurological outcome. Furthermore silent brain lesions are not well documented after endovascular and surgical treatment of unruptured intracranial aneurysms. Therefore, the investigators investigate the incidence and influence of treatment-related ischemic lesions in magnetic resonance / diffusion-weighted-imaging after endovascular and surgical treatment of UIA.

Study Timeline

• Study Start: 2011-08
• Study First Submitted: 2011-12-12
• Study First Submitted QC: 2011-12-12
• Study First Posted: 2011-12-13
• Status Verified: 2013-01
• Primary Completion: 2013-01
• Study Completion: 2013-01
• Last Update Submitted: 2013-01-28
• Last Update Posted: 2013-01-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• diagnosis and treatment of unruptured intracranial aneurysm
• age ≥ 18 yrs
• written informed consent by patients prior to study participation
• willingness to participate in follow-up

Exclusion Criteria

• ruptured intracranial aneurysm
• contraindication for MRI
• Participation in an intervention-/AMG-study

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Department of Neurosurgery, Goethe-University; 🇩🇪 Frankfurt am Main, Hessen, Germany