Pre- and Post-operative Brain MRI in Carotid Endarterectomy

Completed

• Conditions: Carotid Artery Stenoses

• Registration Number: NCT04029259
• Lead Sponsor: Oslo University Hospital

Brief Summary

Patients undergoing carotid endarterectomy in the Department of Vascular Surgery at Oslo University Hospital are consecutively included in this evaluation og pre- and postoperative brain MRI.

Detailed Description

Patients undergoing surgery for carotid stenosis in our Department are examined by brain MRI before and after carotid surgery to evaluate the rationale for the MRI. Brain lesions on MRI before and after carotid surgery are registered, and related to clinical findings. The purpose of the study is to evaluate whether brain MRI in relation to carotid endarterectomy gives additional information to clinical findings, and to CT scan of the brain.

Study Timeline

• Study Start: 2005-01-01
• Primary Completion: 2016-12-31
• Study First Submitted: 2017-08-03
• Study Completion: 2017-12-31
• Status Verified: 2019-07
• Study First Submitted QC: 2019-07-21
• Last Update Submitted: 2019-07-21
• Study First Posted: 2019-07-23
• Last Update Posted: 2019-07-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 320

Inclusion Criteria

• Indication for carotid surgery

Exclusion Criteria

• Contraindications to MRI

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brain lesions on MRI	30 days	Lesions on brain MRI representing thromboembolic or hemorrhagic episodes

Secondary Outcome Measures

Name	Time	Method
Time from Transient Ischemic Attack (TIA) or minor stroke to surgery	Days before surgery, maximum 6 months	International guidelines recommends surgery within 14 days after TIA