Analysis of Emotional Factors and Related Molecules Influencing Prognosis in Patients with Intractable chronic Pain using neuro liquid biopsy
Not Applicable
Recruiting
- Conditions
- Chronic pain
- Registration Number
- JPRN-UMIN000047175
- Lead Sponsor
- Kansai Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
Those who have difficulty completing the questionnaire Those who have difficulty in continuing treatment for 8 weeks Other persons deemed inappropriate as research subjects by the principal investigator.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation of miRNA expression in neuro-derived exosomes with the rate of change in the catastrophic thinking scale before and after treatment of chronic pain patients across groups.
- Secondary Outcome Measures
Name Time Method 1) Comparison of miRNA expression in nerve-derived exosomes between a group of healthy subjects without chronic pain and a group of patients with chronic pain 2) Examination of the relationship between clinical assessment measures and exosomal proteins and miRNAs based on omics analysis and pre- and post-treatment correlations of the following items For the clinical evaluation scale, the following items will be calculated from the questionnaire in addition to the basic patient information