ormal values for echocardiography with speckle tracking and biomarkers in a healthy population.

Completed

• Conditions: heart function; ventricular function; 10082206

• Registration Number: NL-OMON39015
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 140

Inclusion Criteria

Healthy adults between the age of 20 and 70 years.
Capable of understanding and signing informed consent.

Exclusion Criteria

Cardiovascular disease.
Cardiovascular risk factors, such as hypertension, diabetes mellitus, hypercholesterolaemia.
Non-Dutch speaking.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Determining normal values of LV and RV radial, circumferential and longitudinal<br /><br>strain, and LV rotation and twist by speckle-tracking echocardiography in<br /><br>various age groups.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Determining normal values of the biomarkers NT-proBNP, hsCRP, hsTnT, IL-1,<br /><br>IL-6, TNF-a, MMP-2, MMP-9, TIMP-1, GDF-15, HSP-70 in various age groups.</p><br>