NCT00276770已完成不适用
NCI-Sponsored Trial for the Evaluation of Safety and Preliminary Efficacy Using [F18] Fluorothymidine (FLT) As a Marker of Proliferation in Patients With Primary Brain Tumors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
研究概览
简要总结
RATIONALE: Diagnostic procedures, such as positron emission tomography using fluorothymidine F 18, may be effective in finding recurrent disease in patients with gliomas.
PURPOSE: This clinical trial is studying how well positron emission tomography using fluorothymidine F 18 works in finding recurrent disease in patients with gliomas.
详细描述
OBJECTIVES:
Primary
- Determine the safety of fluorothymidine F 18 for visual and dynamic brain tumor images in patients with glial neoplasms.
- Determine, preliminarily, the efficacy of this drug.
Secondary
- Compare, preliminarily, the efficacy of this drug to fludeoxyglucose F 18 in differentiating tumor recurrence from radiation necrosis.
- Determine the optimal time to image post injection of this drug.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究者
研究点 (2)
Loading locations...
相似试验
招募中
1 期
[18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast CancerAnatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaNCT06502691University of Washington22
已完成
早期 1 期
18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing SarcomaAdult Supratentorial Primitive Neuroectodermal Tumor (PNET)Ewing Sarcoma of BoneExtraosseous Ewing SarcomaLocalized Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorMetastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorUntreated Childhood Supratentorial Primitive Neuroectodermal TumorNCT01825902Mayo Clinic1
No Longer Available
不适用
F18 DCFPyL PET/CT in Imaging Participants With Recurrent Prostate CancerProstate AdenocarcinomaPSA Level Greater Than 0.2PSA Level Greater Than or Equal to TwoPSA ProgressionRecurrent Prostate CarcinomaNCT03501940Andrei Iagaru
已完成
1 期
Positron Emission Tomography Before Surgery in Evaluating Women With Primary or Recurrent Breast CancerBreast CancerNCT00039286Memorial Sloan Kettering Cancer Center118
撤回
早期 1 期
Fluorothymidine F-18 PET in Diagnosing Patients With Intermediate or High Grade Soft Tissue SarcomaStage II Adult Soft Tissue SarcomaStage IIA Adult Soft Tissue SarcomaStage IIB Adult Soft Tissue SarcomaStage IIC Adult Soft Tissue SarcomaStage III Adult Soft Tissue SarcomaStage IV Adult Soft Tissue SarcomaNCT03613259OHSU Knight Cancer Institute