A comparison between the hyperbaric solutions of ropivacaine and levobupivacaine for spinal anaesthesia in lower limb orthopaedic surgeries
Phase 4
- Registration Number
- CTRI/2024/03/064415
- Lead Sponsor
- Dr. Rudranka Basu
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients undergoing lower limb orthopaedic surgeries under spinal anaesthesia.
2. Age 18-60 years
3. ASA 1 and 2
4. All genders
5. Patients posted for surgeries with expected duration less than 3 hours
Exclusion Criteria
1. Patient refusal
2. History of allergic reactions to Local Anaesthetics
3. Coagulopathy
4. History of neurological disorders
5. Severe cardio, respiratory, hepatic and renal disease
6. Patients with spinal deformity
7. Patients with previous spinal surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Aim- To compare the duration of analgesia between 0.75% hyperbaric ropivacaine and 0.5% hyperbaric levobupivacaine for spinal anaesthesia in patients undergoing lower limb orthopaedic surgeries <br/ ><br> <br/ ><br>Objective- <br/ ><br>1. To compare the onset of sensory block in two drugs. <br/ ><br>2. To compare the onset of motor block in two drugs. <br/ ><br>Timepoint: Onset and time taken for regression of sensory and motor block will be recorded after every 3 minutes for the first 15 minutes after injection then every 5 minutes for the next 25 minutes and at 60, 90, 120, 180, 240, 300, 360, 420, 480 minutes. Duration of analgesia was assessed using Numerical Rating Scale at 2, 4, 6 and 12 hours in the post-operative period.
- Secondary Outcome Measures
Name Time Method 1. To compare the effect of the two drugs on hemodynamic parameters. <br/ ><br>2. To evaluate any adverse effects.Timepoint: Heart rate and Blood pressure will be monitored at every 5 minutes interval till 15 minutes followed by every 15 minutes interval till 90 minutes and then at every 30min interval.