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Inhibin B – Evaluation of laboratory reference values in children and adolescents as well as a statement to validity and clinical appliance in pediatric diabetology and pediatric cancer survivors

Conditions
study for standard/normal values
E10.90
E89.9
Follow-up examination after unspecified treatment for malignant neoplasm
Z08.9
Postprocedural endocrine and metabolic disorder, unspecified
Registration Number
DRKS00015263
Lead Sponsor
KKJM, UK FfM
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
200
Inclusion Criteria

including criteras:
• informed consent
• Aged < 20 years
• no other relevant disease
• patients with Diabetes mellitus
• patients after cancer therapy, as well as after stem cell transplantation

Exclusion Criteria

excluding criterias:
• aged = 20 years at start of study
• acute disease
• other chronic disease (HIV, Tbc)
• pregnancy
• substance abuse
• parents beeing unable to understand the subject of the study
• participation in another AMG study

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
In this study standard values for Inhibin B will be described as well as an interpretation will be given for Inhibin B in chronic health conditions of pediatric patients with diabetes mellitus and in young survivors of childhood cancer disease. The newly developed Assay „Inhibin B Gen II ELISA may differentiate between structural subgroups of Inhibin B and perform a more accurate measurement since before. <br>
Secondary Outcome Measures
NameTimeMethod
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