The hemodynamic and pulmonary effects of acute high altitude exposure at rest and during exercise in patients with complex congenital heart diseases
Completed
- Conditions
- congenital heart disease10010394
- Registration Number
- NL-OMON46314
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Children and adults with complex congenital heart disease between 8 years and 40 years of age and apparently helathy peers are eligible.
Exclusion Criteria
* Unstable cardiac function (hemodynamic instable irregular heart rate and blood pressure)
* Fever
* Mental or physical disabled patients not able to perform an exercise stress test on a cycle ergometer
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The hemodynamic and pulmonary effects of acute high altitude exposure. Blood<br /><br>pressure, heart rate, exercise capacity, saturation, cardiac output, peak O2<br /><br>uptake en ventilation will be monitored. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The association between desaturation and decrease in exercise capacity will be<br /><br>studied as a secondary objective.</p><br>