MRI investigation of blood flow and regulation to the brain by the neck vessels.
- Conditions
- steno-occlusive disease of the vertebral and basilar artery.
- Registration Number
- NL-OMON28879
- Lead Sponsor
- niversity Medical Center UtrechtDepartment of Radiology (HP E.01.132)PO-Box 855003508 GA Utrecht
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
1. 18 years or older;
2. Patients with ischaemic stroke or TIA in the perfusion territory of the vertebo-basilar arteries.
Exclusion Criteria
1. Pregnancy or possible pregnancy;
2. Implanted stent(s);
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome is cerebrovascular reactivity measured with MR imaging at 3 Tesla using a visual stimulus and administration of vasodilatory challenge medication to induce hemodynamic stress.
- Secondary Outcome Measures
Name Time Method Secondary outcomes include cerebral blood flow and perfusion territories of the brain feeding arteries.