Dose Titration of Propofol for Tracheal Intubation in Children With Sevoflurane Inhalation Induction

Not Applicable

Completed

• Conditions: Pediatric Urinary Disorders
• Interventions: Drug: propofol

• Registration Number: NCT01084031
• Lead Sponsor: Yonsei University

Brief Summary

Dose titration of propofol for tracheal intubation in children with sevoflurane inhalation induction.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-11
• Primary Completion: 2010-02
• Study First Submitted: 2010-03-05
• Study First Submitted QC: 2010-03-09
• Study First Posted: 2010-03-10
• Study Completion: 2011-03
• Status Verified: 2014-02
• Last Update Submitted: 2014-02-17
• Last Update Posted: 2014-02-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Pediatric patients scheduled for elective day case surgery were enrolled.

Exclusion Criteria

• History of obstructive sleep apnea
• Evidence of cardiorespiratory disease
• Those who were obese or allergic to any of the anesthetic agents in this study
• Those with an anticipated difficult airway, full stomach
• History of malignant hyperthermia or other myopathy were excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
propofol	propofol	-

Primary Outcome Measures

Name	Time	Method
Assessment of intubation conditions	30 minutes after the surgery	Assessment of intubation conditions (vocal cord, intubation condition, cough, movement) , peri-induction HR and BP change, post-operative agitation socre at recovery room. ED50 and ED 95 of each group by uring Dixon's up and down methods.; peri -induction period -comparison of above factors among each groups (GroupA: ETSevo 3vol%, Group B: ETSevo 3.5vol%, Group: ET Sevo 4vol%)