Electroencephalography-based investigation of the effects of oral desmopressin on improving slow-wave sleep time in nocturnal polyuria patients

Phase 4

Recruiting

• Conditions: octuria due to nocturnal polyuria; nocturia, nocturnal polyuria; D053158

• Registration Number: JPRN-jRCTs051190080
• Lead Sponsor: Torimoto Kazumasa

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-12-09
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

1 Nocturnal urinary frequency = and >2 and Nocturnal polyuria index (nocturnal urinary volume/24 hours urinary volume) = and >0.33
2 Hours of undisturbed sleep before registration = and <2.5 hours
3 Concentration of serum sodium = and >135 mEq/L
4 Creatinine clearance or eGFR (estimate glomerular filtration rate) = and >50 mL/min/1.73m^2

Exclusion Criteria

1 Hyponatremia or the history (Concentration of serum sodium <135 mEq/L)
2 Habitual or Psychogenic polydipsia
3 Heart failure or the history or suspected heart failure
4 Fluid retention that requires diuretic treatment or the history
5 Antidiuretic hormone incompatible secretion syndrome
6 Moderate or severe renal failure (Creatinine clearance or eGFR <50 mL/min/1.73m^2)
7 Hypersensitivity to desmopressin or the history
8 During or scheduled administration of thiazides, thiazide-like diuretics, loop diuretics
9 During or scheduled administration of corticosteroids
10 Carciac pacemaker implantation
11 Judged to be inappropriate by the principal Investigator or subinvestigators

Study & Design

• Study Type: Interventional
• Study Design: Not specified