Comparison of Isobaric 0.75 Ropivacaine with fentanyl versus Hyperbaric 0.5 Bupivacaine with fentanyl in Spinal anaesthesia for infraumbilical surgeries.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To compare the hemodynamic changes associated with isobaric 0.75% ropivacaine with fentanyl versus hyperbaric 0.5% bupivacaine with fentanyl during spinal anesthesia for infraumbilical surgery.
研究概览
简要总结
Spinal anesthesia is a preferred technique for infraumbilical surgeries due to its effectiveness and safety profile. While bupivacaine is commonly used, ropivacaine has emerged as a potential alternative, offering a favorable cardiovascular safety profile. This study aims to compare the hemodynamic changes, onset duration, quality of sensory and motor blockade, and adverse drug reactions between isobaric 0.75% ropivacaine with fentanyl and hyperbaric 0.5% bupivacaine with fentanyl.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Elective infraumbilical surgical procedures
- •Surgical duration anticipated to be within 2 hours 30 minutes.
排除标准
- •Patients with bleeding disorders
- •ASA III and IV patients.
结局指标
主要结局
To compare the hemodynamic changes associated with isobaric 0.75% ropivacaine with fentanyl versus hyperbaric 0.5% bupivacaine with fentanyl during spinal anesthesia for infraumbilical surgery.
时间窗: Before Induction, During Induction, 3 minutes, 6 minutes, 9 minutes, 12 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes, 45 minutes, 60 minutes, 75 minutes, 90 minutes, 105 minutes, 120 minutes, 135 minutes, 150 minutes, 165 minutes, 180 minutes.
次要结局
- 1. To compare the duration of onset of sensory and motor blockade between the two anesthetic combinations.(2. To assess the quality of sensory and motor blockade provided by each anesthetic regimen.)
研究者
Dr Deepak R
BJ govt medical college, Pune