Study the Effect of Neurectomy of Nasopalatine Nerve on Sensation of Anterior Palate

Not Applicable

• Conditions: Missing Teeth
• Interventions: Procedure: neurectomy of nasopalatine nerve

• Registration Number: NCT04153851
• Lead Sponsor: Cairo University

Brief Summary

Study the effect of neurectomy of nasopalatine nerve on the sensation of anterior palate in patients undergoing rehabilitation of anterior maxillary ridge with dental implant

Detailed Description

Replacement of missing teeth in the anterior maxilla could be challenging if enlargement of the nasopalatine canal which is located in the midline of the palate posterior to the maxillary central incisors or ridge atrophy occur after tooth extraction. This could place the neurovascular content of the nasopaltine canal in the path of the dental implant which may lead to complications such as nasopalatine canal cyst, sensory dysfunction or implant failure. Technique to overcome this problem have evolved including neurectomy of the nasopalatine canal content and obliteration of canal with bone graft.

Loss of sensation in anterior palate following this procedure could be an annoying complication for patients. In recent studies regaining of sensation following such procedure have been reported, Confirmation of such results is essential to rule out the side effect of loss of sensation in the anterior palatal region

Study Timeline

• Status Verified: 2019-11
• Study First Submitted: 2019-11-02
• Study First Submitted QC: 2019-11-05
• Study First Posted: 2019-11-06
• Last Update Submitted: 2019-11-06
• Last Update Posted: 2019-11-08
• Study Start: 2019-12-01
• Primary Completion: 2020-12-31
• Study Completion: 2021-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

• • Adult patients requiring dental implants placement in the anterior region of maxilla and has insufficient horizontal bone .

  • Patients should be free from any systemic conditions that may affect soft tissue healing.

Exclusion Criteria

• • Patients with systematic disease that may complicate healing.

  • Uncontrolled diabetic patient.
  • Patients with advanced osteoporosis.
  • Patients under bisphosphonates treatment.
  • Patients with neurological disorders (neuralgias, Parkinson's disease).
  • Patients with horizontal ridge atrophy (if the horizontal dimension of the residual ridge <3mm as determined with ridge callipers).
  • Heavy smoker patients.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
neurectomy of nasopalatine nerve	neurectomy of nasopalatine nerve	1. Prophylactic preoperative antibiotic will be administered prior to surgery. 2. Oral disinfection will be performed before surgery. 3. Labial infiltration anesthesia and nasopalatine nerve block anasthesia. 4. The nasopalatine foramen will be exposed after reflection of a palatal and buccal flap. 5. Severing of nerurovascular bundle and pushing the nasopalatine canal content nasally and insertion of bone graft in the canal. 6. Dental implant will be inserted in the central incisor location.

Primary Outcome Measures

Name	Time	Method
two point discrimination test	six months	This test will be performed using a calliper, the two points of the calliper are opened progressively in 1mm increments and care should be taken that the two points are touching the mucosa in the same time until the patient can discriminate two points of contact at which the distance between the two points is recorded

Trial Locations

Locations (1)

Cairo university; 🇪🇬 Cairo, Egypt