To study the difference in effect of various drug in patient suffering from Schizophrenia, a kind of mental disorder in which signs and symptoms are variable and include changes in perception, emotion, cognition, thinking, and behaviour.
- Conditions
- Health Condition 1: F200- Paranoid schizophreniaHealth Condition 2: null- Schizophrenia
- Registration Number
- CTRI/2018/02/011813
- Lead Sponsor
- Department of Pharmacology and therapeutics
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 54
Diagnosis of Schizophrenia as per ICD-10, DCR, Patients aged between 18 to 50 years, Not on any antipsychotic for last three months, Total duration of illness less than one year, Availability of a reliable informant, Written informed consent from the patient/legally acceptable representative
Positive and Negative Syndrome Scale (PANSS) score <80 or >120, Presence of any other major psychiatric disorder, except nicotine dependence, Patients at risk for harm to self or others, Established treatment resistance for schizophrenia, Pregnant and lactating females, Clinical situations requiring drugs which are CYP 3A4/2D6 inhibitors or inducers, Clinical situations requiring alternative drugs or interventions eg injectable antipsychotics, ECTs, change of therapy etc., or worsening of symptoms, Patients having any major medical/surgical illness or any clinically significant abnormality in baseline investigations, Patient on any other concomitant drugs that might alter serum interleukin levels
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method