Do the effects of orenatal famine exposure pass down generations? An epigenitic study.

• Conditions: cardiovascular disease; 10011082; 10018424; 10034726

• Registration Number: NL-OMON31890
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 2580

Inclusion Criteria

Men and women born at the time of the Dutch Famine 1944-1945 in the Wilhelmina Gasthuis in Amsterdam, their mothers(F0) and children(F2).

Exclusion Criteria

NVT

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary outcome: % methylation of the CpG regions of 4 candidategenes.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcome: health of F2.</p><br>