Impact of enriched food ration distribution to pregnant women in Maela refugee camp
- Conditions
- utritional status of pregnant and lactating women and role in fetal growth, pregnancy outcomes, infant growth and developmentExposure to pesticides (DDT) and role in fetal growth, pregnancy outcomes, infant growth and development
- Registration Number
- DRKS00007736
- Lead Sponsor
- Oxford University, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine Research Building,
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 1164
Inclusion Criteria
reproductive age group;
offspring of women enrolled in the observational study
Exclusion Criteria
Pregnant women not having access to the refugee food ration.
Pregnant women or lactating mothers with a hematocrit below 20%.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary endpoint: Comparison of nutritional status of the mother (at each trimester of pregnancy) before and after the introduction of the enriched flour; hematocrit and micronutrient status in blood (iron, zinc, vitamin A/E/B1) were measured in two sequential cross-sectional studies - the first survey was conducted before and the second survey two years after the introduction of micronutrient fortified flour as a new food ration in the camp
- Secondary Outcome Measures
Name Time Method Secondary endpoint 1: Comparison of nutritional status (prevalence of anaemia, vitamin deficiency and mean vitamin/micronutrient levels in blood and breast milk) in pregnancy and during breast feeding.<br><br>Secondary endpoint 2: Comparison of foetal growth and pregnancy outcome<br>(prevalence of low birth weight, small-for-gestation, premature, mean<br>anthropometric measurements) before and after the introduction of the enriched flour.<br><br>Secondary endpoint 3: Comparison of the DVM prevalence in children born to mothers who did not receive the flour and those who did and controlled for DDT exposure.<br><br>Secondary endpoint 4: Comparison of growth (i.e. prevalence of stunting, underweight) and cognitive development according to DDT exposure in utero.<br><br>