Body composition, nutrition & outcomes after neoadjuvant chemotherapy

Not Applicable

Completed

• Conditions: pper Gastro-Intestinal Cancer; Oesophagus, Stomach; Cancer; Malignant neoplasm of oesophagus and stomach

• Registration Number: ISRCTN15674981
• Lead Sponsor: niversity of Nottingham (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03-13
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Age 18 - 80 years
2. Confirmed oesophageal or gastric (adenocarcinoma or squamous cell) carcinoma in patients due to undergo neoadjuvant chemotherapy
3. Able to give informed consent and comply with study protocol

Exclusion Criteria

1. Patients with GIST tumours
2. Presence of severe organ specific disease (e.g. heart/respiratory/renal/liver failure)
3. Presence of inherited metabolic disorders
4. Simultaneous participation in another clinical study
5. Patients with suspicion of alcohol/drug abuse
6. Diabetes mellitus or other endocrine disorders (e.g. thyroid disease, Cushing?s syndrome)

For second study cohort receiving INSP:
1. Allergy to any constituent of the nutritional supplements
2. Total dysphagia (inability to take oral liquids or solids)
3. Clinical evidence of aspiration

Study & Design

• Study Type: Interventional
• Study Design: Not specified