Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure

Recruiting

• Conditions: Acute Respiratory Failure

• Registration Number: NCT05347563
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Electrical impedance tomography (EIT) is a non-invasive, bedside monitoring technique that provides continuous, real-time information about the regional distribution of the ventilation.

There are very few data in children admitted to the PICU (pediatric intensive care unit) and the aim of the study is to describe the distribution of the ventilation in children with acute respiratory failure and to study the impact of the interventions in the PICU (change in ventilatory settings, change in position, suction, respiratory kinesiotherapy,...)

Detailed Description

Children with acute respiratory failure admitted to the PICU (pediatric intensive care unit)

Study Timeline

• Study First Submitted: 2022-04-12
• Study First Submitted QC: 2022-04-25
• Study First Posted: 2022-04-26
• Study Start: 2022-06-18
• Status Verified: 2024-03
• Last Update Submitted: 2025-02-19
• Last Update Posted: 2025-02-20
• Primary Completion: 2027-06
• Study Completion: 2027-06

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

Groupe A

• children < 18 years
• Admitted to the PICU with acute respiratory failure
• Monitoring with EIT
• non opposition of parents or legal representative Groupe B
• children < 18 years
• With general anesthesia and mechanical ventilation
• Monitoring with EIT
• non opposition of parents or legal representative

Exclusion Criteria

• Monitor not available
• contra indication to the use of thoracic belt
• Intraoperative period with use of electrocautery
• Child not affiliated to a social security system and under protective measures legal

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Distribution of Ventilation	up to 48 hours	Distribution of ventilation as determined by changes in impedence in region of interest

Trial Locations

Locations (3)

Hôpital Femme Mère Enfant Service de néonatologie et réanimation néonatale; 🇫🇷 Bron, Rhone, France

Hôpital Femme Mère Enfant Service de réanimation et d'urgence pédiatrique; 🇫🇷 Bron, Rhone, France

Paediatric intensive care Unit; 🇫🇷 Bron, Rhone, France