Comparison Between Combined Regional Nasal Block and General Anesthesia Versus General Anesthesia With Dexmedetomidine During Endoscopic Sinus Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Optimizing intraoperative surgical field
研究概览
简要总结
The purpose is to compare the efficacy of combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery in optimizing intraoperative surgical field.
详细描述
This study will be done to compare between two different techniques including regional nasal block and dexmedetomidine in optimizing intraoperative surgical field according to average category scale
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients of ASA I or ASA II physical status.
- •Patients with age 18-65 years.
排除标准
- •Patients with physical status ASA III, IV.
- •Known allergic reactions to local anesthetics.
- •Patients with history for cerebrovascular or coronary insufficiency.
- •Patients with infection at the block site.
- •Patients with coagulopathy.
研究组 & 干预措施
regional nasal block
sphenopalatine ganglion block with general anesthesia
干预措施: Bupivacaine HCl 0.5% Injectable Solution (Drug)
dexmedetomidine
use the drug with general anesthesia
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
Optimizing intraoperative surgical field
时间窗: Up to 6 months
Comparison between efficacy of the two techniques in optimizing intraoperative surgical field which will be measured using the average category scale(where grade 0 is defined as no bleeding and grade 5 is defined as severe bleeding, constant suctioning required).
次要结局
- Blood loss in millilitres(Up to 8 months)
- phentolamine requirements in milligrams(Up to 8 months)
- Mean blood pressure in mmHg(Up to 8 months)
- Duration of anesthesia in minutes(Up to 8 months)
- Heart rate in beat per minute(Up to 8 months)
- endtidal sevoflurane concentration in MAC%(Up to 8 months)
- Pain assessment with visual analogue scale(VAS)(Up to 8 months)
- Duration of surgery in minutes(Up to 8 months)