Determination of respiratory mechanics, arterial oxygenation and functional lung ventilation under a prospective change of the end-expiratory pressure in healthy, intubated and mechanically ventilated patients in the prone position.

Not Applicable

• Conditions: intraoperative, controlled ventilation

• Registration Number: DRKS00005692
• Lead Sponsor: Klinik für Anästhesiologie und IntensivmedizinUniversitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2014-02-26
• Study Completion: 2014-09-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

controlled ventialtion, prone position, arterial blood pressure monitoring

Exclusion Criteria

age<18 years, patients refusal, diagnosed lung disease, compromising cardiopulmonal disease, pregnancy, intraoperative oxygenation disorder, emergency operation, overweight (BMI>50), heart pacemaker, heart defibrillator and other active implant, valvular heart disease, language barrier

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Calculation of the respiratory system compliance using airway pressure and tidal volume (measured by volume flow) at each PEEP level

Secondary Outcome Measures

Name	Time	Method
arterial oxygen partial pressure, measured by arterial blood gas sample, one measurement at each PEEP level;<br>functional regional lung ventilation, measured by means of the electrical impedance tomography, one measurement at each PEEP level (5 min.)