Comparison between volume-controlled and pressure-controlled modes of ventilation on respiratory mechanics during laparoscopic surgeries requiring trendelenburg position
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- To compare the tidal volume delivered with its corresponding peak pressure in volume controlled ventilation against the tidal volume delivered at the same set pressure in pressure controlled ventilation. Whether changing the mode of ventilation to PCV during laparoscopic surgeries will result in delivery of desired tidal volume at lower peak airway pressure
研究概览
简要总结
Laparoscopic surgeries in trendelenburg position are known to have certain consequences on respiratory mechanics due to an increase in intra-abdominal pressure during creation of pneumoperitoneum and the subsequent trendelenburg position. One of the most frequently used modes of ventilation in general anaesthesia is Volume Controlled ventilation in which tidal volume is set which may result in high airway pressure. In Pressure controlled ventilation, the inspiratory pressure is set, and the tidal volumes could vary. The decelerating flow pattern in PCV could result in better tidal volume for a set inspiratory pressure, but the same has not been proven.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing laparoscopic surgeries requiring trendelenburg position under general anesthesia, American Society of Anesthesiologists classification I and II.
排除标准
- 未提供
结局指标
主要结局
To compare the tidal volume delivered with its corresponding peak pressure in volume controlled ventilation against the tidal volume delivered at the same set pressure in pressure controlled ventilation. Whether changing the mode of ventilation to PCV during laparoscopic surgeries will result in delivery of desired tidal volume at lower peak airway pressure
时间窗: T1:After intubation | T2: Immediately after creation of pneumoperitoneum in supine position | T3:After 10 minutes of creation of pneumoperitoneum with the patient in surgical position (30-degree head-low) | T4:20 minutes after creation of pneumoperitoneum in surgical position | T5: After desufflation in supine and neutral position
次要结局
- To compare other respiratory parameters like compliance, mean airway pressures in both modes of ventilation(Time point 1: After intubation)
研究者
Dr Ratnala Swetha
Department of Anesthesiology, Kasturba medical college and hospital, Manipal