Post-Menopausal Status and Memory Loss
- Conditions
- Health Condition 1: null- Post Menopausal Women with Impaired Cognitive Function
- Registration Number
- CTRI/2017/11/010403
- Lead Sponsor
- SRM University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 53
1. MMSE Score 21-24
2. Menopausal women (taken as complete cessation of menstruation for at least 1 year/12 cycles) who had attained menopause for a period extending over 4 â?? 10 years at the time of inclusion into the study.
1. MMSE Score 25-30
2. History of recent or current Estrogen or hormonal replacement therapy
3. Known hypertensive, diabetic, renal disease, endocrine disorders, overt nutritional deficiency states, anemia, liver disease or those having history of psychiatric illness.
4. History of Women having estrogen secreting ovarian tumors, for e.g., granulosa and theca cell tumors, tumors of the adrenal gland.
5. Known history of neurological disorders including CVA, space occupying lesions, epilepsy and developmental anomalies.
6. Women, who are physically unable to hear, read or understand written or explained instructions properly, or may have a motor deficit that affects writing and drawing skills.
7. Women, who are already in any of the antioxidant or dietary supplement therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Vitamin B12 and Vitamin C Effects on Cognitive Function will be studiedTimepoint: Baseline, 45 days, 90 days
- Secondary Outcome Measures
Name Time Method Relation between estrogen and cognitive function will be studiedTimepoint: Baseline, 45 days, 90 days