Liver Function Test Abnormalities in COVID-19 Egyptian Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 118
- 试验地点
- 1
- 主要终点
- Percentage of liver function tests abnormalities in Egyptian patients who infected with COVID19 -To evaluate if liver function test abnormalities are related to the severity of the Covid19.
研究概览
简要总结
With the increasing number of COVID-19 infected patients, several studies reported that the liver is the most frequently affected organ after lung damage. The percentage of infected patients who had abnormal levels of transaminases (alanine aminotransferase (ALT) and aspartate aminotransferase (AST)) was about 14.8-53.1%. The elevation in serum bilirubin was mostly mild.
Aims of work:
- To study liver function tests abnormalities in Egyptian patients who infected with COVID19
- To evaluate if liver function test abnormalities are related to the severity of the Covid19.
详细描述
This retrospective study will be conducted on 100 patients who were diagnosed as SARS COVID19 positive. The data will be collected from patient records in COVID19 isolation hospitals in Sohag governorate and isolation department in Sohag university hospitals during the period from the start of June 2020 to the end of July 2020.
The study protocol will be approved by the Scientific Research Ethical Committee, Faculty of Medicine, Sohag University.
Inclusion criteria:
Patients with Covid19 positive PCR.
Exclusion Criteria:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Covid19 positive PCR.
排除标准
- •Patients with chronic liver diseases as liver cirrhosis, Hbs Ag positive, or patients having anti-HCV antibodies positive and HCV RNA positive
结局指标
主要结局
Percentage of liver function tests abnormalities in Egyptian patients who infected with COVID19 -To evaluate if liver function test abnormalities are related to the severity of the Covid19.
时间窗: during the period from the start of June 2020 to the end of July 2020
Liver function test abnormalities among patients with severe and non-severe disease
时间窗: during the period from the start of June 2020 to the end of July 2020
Risk factors of Liver function test abnormalities
时间窗: during the period from the start of June 2020 to the end of July 2020
次要结局
未报告次要终点
研究者
Mona Mohammed Abdelrhman
Principal investigator
Sohag University