Left atrial function in individuals with metabolic syndrome : A cross-sectional study
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Kasturba Medical College Manipal Academy of Higher Education
- Enrollment
- 260
- Locations
- 1
- Primary Endpoint
- Left atrial strain
Overview
Brief Summary
The study will be conducted after obtaining IRC and IEC approval and CTRI registration. After IRC, IEC and CTRI registration, stable participants aged between 30-55 years of age diagnosed with metabolic syndrome according to the NCEP ATP III criteria undergoing transthoracic echocardiography advised by Cardiologists will be recruited in the study. Test details will be explained to the subject and informed consent will be obtained. ECG gated standard views will be acquired using transthoracic echocardiography. Using 2D echocardiography, all the basic parameters including tissue Doppler velocities at septal and lateral wall are obtained. Conventional parameters like LA volume, LA area, LA EF and LA strain will also be obtained. Analysis of LA strain will be done offline using a presently marked semi-automated software Echo PAC version 202.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 30.00 Year(s) to 55.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •All individuals having Metabolic Syndrome between the age group of 30 years to 55 years of age.
Exclusion Criteria
- •Participants with previously diagnosed cardiovascular disease including valvular heart disease ischemic heart disease previous cardiac surgery or percutaneous interventions.
Outcomes
Primary Outcomes
Left atrial strain
Time Frame: At baseline
Left atrial volume index
Time Frame: At baseline
Secondary Outcomes
- Left atrial volume(Left atrial area)
Investigators
N Neethu Pai
Manipal College of Health Profession