Study to Evaluate the Effect of Injection Lypolysis (Lipodissolve) Treatments to Reduce Body Fat
- Conditions
- Abdominal Subcutaneous Fat
- Interventions
- Registration Number
- NCT00757081
- Lead Sponsor
- BodyAesthetic Research Center
- Brief Summary
The combination of phosphatidylcholine (PPC) and deoxycholate (DC) injected into subcutaneous fat is often popularly referred to as "Lipodissolve" therapy. Despite its attractiveness as an easy and noninvasive cosmetic treatment, the safety, effectiveness, and how the injections might work remain unclear. This study will investigate the hypothesis that injections of PPC/DC will reduce the amount body fat in the treated area. If so, the mechanisms responsible for the fat loss will be explored to find out whether fat cells die from toxic effects or are broken apart by the PPC/DC. Patients will receive at least 2 (no more than 4) treatments with PPC/DC injections every 2 months. Several methods of measuring fat loss will be used in the study, including photography and measurement of patients, tissue biopsy, blood tests, and MRI. The study will also record side effects of the treatments as well as patient satisfaction.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
- Healthy volunteer
- Body Mass Index (BMI) no greater than 30
- Excess fat in the lower abdomen area
- Cigarette smoker
- Diabetes
- Pregnant or breast feeding
- Use anticoagulants (blood thinner), aspirin or other non-steroidal anti-inflammatory drugs that cannot be discontinued
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 1 phosphatidylcholine and deoxycholate -
- Primary Outcome Measures
Name Time Method Subcutaneous fat thickness with calipers and MRI. Before and 8 weeks after final treatment
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
BodyAesthetic Research Center
🇺🇸Creve Coeur, Missouri, United States