Plasma lipoproteins in coronary artery disease.
Not Applicable
Active, not recruiting
- Conditions
- Coronary artery diseaseAssociation of plasrma lipoproteins in atherosclerotic and atherothrombotic coronary artery disease.Cardiovascular - Coronary heart disease
- Registration Number
- ACTRN12616001312437
- Lead Sponsor
- St George Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 795
Inclusion Criteria
All patients recommended to have CT coronary angiography or coronary angiography will be recruited.
Pre specified subgroup analysis will be performed based upon angiographic findings and clinical presentation.
Willing to provide informed consent.
Exclusion Criteria
1.Severe valvular disease.
2.Thrombolysis in last one week
3.Previously enrolled in this study
4.Active sepsis
5.Nephrotic syndrome
6.End stage renal failure on dialysis
7.Severe liver disease (Child-Pugh C)
8.Current pregnancy
9.Previously documented Antiphospholipid Antibody Syndrome
10.Active malignancy
11.Cerebrovascular accident in the last 3 months
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation of beta-2-glycoprotein I, HDL and APOB100 on serum ELISA with the extent of coronary artery disease.<br>This shall be assessed both as multiple separate outcomes and composite outcomes.<br>The extent of coronary artery disease shall be measured with SYNTAX Score.<br>[Cross-sectional at the time of angiography.];Correlation of beta-2-glycoprotein I, HDL and APOB100 on serum ELISA with clinical presentation.<br>Again, this shall be assessed both as multiple separate outcomes and composite outcomes.<br>Clinical presentation is assessed by history taking, examination, ECG and troponin elevation.[Cross-sectional at the time of angiography.]
- Secondary Outcome Measures
Name Time Method