Feasibility Study Using Functional Magnetic Resonance Imaging (fMRI) on Bordeline Personality Disorders in Adolescents
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- MRI-Acquired Activation Mapping
研究概览
简要总结
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents with BPD. This study aims to increase knowledgements related to neural correlates of BPD and clinical disorders.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 12 Years 至 17 Years（Child）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female adolescents meeting DIB-R criteria for BPD group
- •Female adolescents meeting kSADS-PL for ADHD group
- •Female adolescents without any psychologic disorders
排除标准
- •Any medical history with head trauma, chronic neurologic disease, any contraindications for fRMI, claustrophobia or pregnancy.
研究组 & 干预措施
Healthy adolescent girl volunteers
The participants will follow the same study plan
干预措施: functional magnetic resonance imaging (fMRI) (Diagnostic Test)
Adolescent girls with borderline personality disorder
The participants will follow the same study plan
干预措施: functional magnetic resonance imaging (fMRI) (Diagnostic Test)
Adolescent girls with Attention Deficit Hyperactivity Disorder
The participants will follow the same study plan
干预措施: functional magnetic resonance imaging (fMRI) (Diagnostic Test)
结局指标
主要结局
MRI-Acquired Activation Mapping
时间窗: 2 years
Establishment of activation maps by statistical analysis of local signal variations to locate functional regions essential to motor skills and language.
次要结局
- Feasibility of this study(2 years)