The Effect of Preoperative Ketamine on the Emergence Characteristics in Children Undergoing Entropion Surgery

Not Applicable

Completed

• Conditions: Entropion
• Interventions: Drug: Sevoflurane; Drug: Desflurane

• Registration Number: NCT02916407
• Lead Sponsor: Inje University

Brief Summary

The investigators evaluate extubation time and recovery profiles in children undergoing entropion surgery.

Detailed Description

This study will compare the extubation time and recovery profiles (degree of postoperative agitation and cough) between sevoflurane group and desflurane group. General anesthesia will maintained with sevoflurane 2-3vol% or desflurane 6-7vol%. After surgery, the investigators will measure the duration of extubation and recovery profiles between two groups.

Study Timeline

• Study Start: 2016-09
• Study First Submitted: 2016-09-01
• Study First Submitted QC: 2016-09-24
• Study First Posted: 2016-09-27
• Primary Completion: 2017-11
• Study Completion: 2017-11
• Results First Submitted: 2018-12-14
• Status Verified: 2019-04
• Results First Submitted QC: 2019-04-29
• Last Update Submitted: 2019-04-29
• Results First Posted: 2019-05-03
• Last Update Posted: 2019-05-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• American society of anesthesiologist class 1 patients
• 3-6 years children undergoing entropion surgery

Exclusion Criteria

• Do not agree with participate this study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Sevoflurane Group	Sevoflurane	The patients will maintained general anesthesia with sevoflurane.
Desflurane Group	Desflurane	The patients will maintained general anesthesia with desflurane.

Primary Outcome Measures

Name	Time	Method
Extubation Time	30 minutes	compare the extubation time between sevoflurane and desflurane group

Secondary Outcome Measures

Name	Time	Method
Degree of Postoperative Agitation	30 minutes	Postoperative agitation will measure using Pediatric Anesthesia Emergence Delirium (PAED) scale. PAED scale is "(1) The child makes eye contact with the caregiver (2) The child's action are purposeful (3) The child is aware of his/her surrounding (4) The child is restless (5) The child is inconsolable." It scores 0-4, and total maximum score is 20.; PAED score \> 12 was used to determine occurence of postoperative agitation.

Trial Locations

Locations (1)

Haeundae paik hospital, inje university; 🇰🇷 Busan, Korea, Republic of