Measurement of blood flow time in carotid artery by ultrasound and to assess its predictability in assessing intravenous fluid response in patients admitted with hypotension

Not yet recruiting

• Conditions: Other hypotension,

• Registration Number: CTRI/2022/03/040761

Brief Summary

Fluids are being administered for resuscitation to increase intravascular volume thereby increasing cardiac output and blood pressure in patients admitted with hypovolemic/septic shock. Multiple methods have been recommended to assess fluid responsiveness. Measurement of changes in Corrected Carotid flow time (cCFT) is one of the non-invasive techniques to assess the changes in fluid status using bedside ultrasonography. In this study, we aim to evaluate the role of Corrected Carotid Flow Time measured by ultrasonography in predicting fluid responsiveness in patients presenting with undifferentiated shock.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-02-25
• Study Start: 2022-03-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

New onset Septic/Hypovolemic shock.

Exclusion Criteria

• BMI >30 kg/m2.
• Cardiac arrhythmia Valvular heart disease Cardiomyopathy Carotid artery stenosis COPD Symmetric anterior bilateral B lines on Lung Ultrasonography Poor transthoracic window Cardiogenic/obstructive shock Patients on vasopressor therapy.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Corrected carotid flow time as a predictor of fluid responsiveness in patients presenting with septic/hypovolemic shock	Baseline | Post first fluid bolus

Secondary Outcome Measures

Name	Time	Method
Correlation between corrected Carotid flow time, Lung USG values and Stroke volume during initial fluid resuscitation of patients presenting with septic/hypovolemic shock	Baseline and after each fluid bolus
Comparison of baseline variables among the responders versus non-responders to fluid resuscitation	Baseline
Incidence of repeat hypotension, need of vasopressors and total fluid administered among responders versus non-responders to fluid resuscitation, in patients presenting with septic or hypovolemic shock	First 24 hours

Trial Locations

Locations (1)

AIIMS, Rishikesh; 🇮🇳 Dehradun, UTTARANCHAL, India

AIIMS, Rishikesh

🇮🇳Dehradun, UTTARANCHAL, India

Davis Cherian

Principal investigator

9843690069

cherian.davis@gmail.com