Viscosity of Fibre Predicts Cholesterol-lowering in Healthy Individuals

Phase 2

Completed

• Conditions: Lipidemia; Healthy

• Registration Number: NCT03741621
• Lead Sponsor: Unity Health Toronto

Brief Summary

To investigate the role of fibre viscosity (low, medium, high) in lowering cholesterol in healthy individuals

Detailed Description

Not available

Study Timeline

• Study Start: 1992-01
• Primary Completion: 1994-01
• Study Completion: 2010-07
• Status Verified: 2018-11
• Study First Submitted: 2018-11-07
• Study First Submitted QC: 2018-11-13
• Last Update Submitted: 2018-11-13
• Study First Posted: 2018-11-15
• Last Update Posted: 2018-11-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

-healthy individuals

Exclusion Criteria

• regular alcohol consumption
• regular smoking

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
change in LDL cholesterol	change from baseline after 21 days, relative to control

Secondary Outcome Measures

Name	Time	Method
change in apolipoprotein A-1	change from baseline after 21 days, relative to control
change in HDL cholesterol	change from baseline after 21 days, relative to control
change in total cholesterol	change from baseline after 21 days, relative to control
change in apolipoprotein B	change from baseline after 21 days, relative to control
change in triglycerides	change from baseline after 21 days, relative to control