跳至主要内容
临床试验/ISRCTN11185706
ISRCTN11185706暂停未知

Problem adaptation therapy for individuals with mild to moderate dementia and depression: the PATHFINDER trial

OCLOR0 个研究点目标入组 336 人开始时间: 2018年5月31日最近更新:

试验速览

阶段
未知
状态
暂停
发起方
入组人数
336

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Diagnosis of probable AD or mixed AD and vascular dementia using NIA-AA criteria
  • 2. Mild to moderate dementia severity, defined by an SMMSE score >10
  • 3. Clinically significant depression, defined by score of 8+ on the Cornell Scale for Depression in Dementia
  • 4. Aged >50 years
  • 5. Sufficiently fluent in English to engage with the PATH intervention
  • 6. Identified family carer who spends >1 hour per day on at least 3 days per week with participant and agrees to act as co-therapist for intervention

排除标准

  • 1. Diagnosis of rarer dementias, including dementia with Lewy bodies, Parkinson’s disease dementia and frontotemporal dementia
  • 2. Initiation of prescription or change in dose of antidepressant or other psychotropic medication in previous 4 weeks or plan to change treatment during the next 12 weeks
  • 3. Those currently engaged in formal psychological therapy
  • 4. Those requiring treatment for a severe psychiatric disorder such as schizophrenia or bipolar disorder
  • 5. Are severely depressed and expressing suicidal ideation with active plans/suicidal behaviours and intent, as other forms of treatment and support would be indicated

研究者

发起方
OCLOR

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