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A study of R435(Bevacizmab) Added to Various Chemotherapy Regimens in Patients With Colon Cancer

Phase 3
Conditions
Colon cancer
Registration Number
JPRN-jRCT2080220307
Lead Sponsor
Chugai Pharmaceutical Co., Ltd.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Sex
All
Target Recruitment
Not specified
Inclusion Criteria

- >= 18 years of age, adult patients
- documented colon carcinoma
- not a candidate for (neo) adjuvant radiotherapy
- curative surgery not less than 4 and not more than 8 weeks prior to study randomization.
Exclusion criteria:
- evidence of metastatic disease
- previous anti-angiogenic treatment for any malignancy
-previous cytotoxic chemotherapy, radiotherapy, or immunotherapy for colon cancer
- pregnant or lactating women
- fertile men, or women of childbearing potential, not using adequate contraception
- major surgical procedures, open biopsy, or significant traumatic injury, within 28 days prior to study treatment start
- current or recent treatment (within 28 days prior to randomization) with another investigational drug, or participation in another investigational study

Exclusion Criteria

Not provided

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Disease -free survival,
Secondary Outcome Measures
NameTimeMethod
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